Manager - RWE Innovation Programming

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

The Center for Observational Research (CfOR) generates real-world evidence to support Amgen’s medicines throughout their lifecycle. The newly formed Programming Innovations Team builds on that foundation—developing, implementing, and maintaining programming solutions, tools, and processes that improve efficiency, quality, and scalability across CfOR.

As a Manager on the Programming Innovations Team, you will play a key role in identifying opportunities for improvement, designing and delivering solutions, and fostering innovation that accelerates real-world data (RWD) analytics across Amgen.

NOTE: THIS ROLE DIFFERS FROM A TRADITIONAL STATISTICAL PROGRAMMING POSITION.
This position will focus on developing programming efficiencies, automation solutions, and innovative tools that enhance productivity and scalability across programming teams. This position is ideal for candidates who enjoy building systems and optimizing workflows—not for those primarily seeking to perform statistical analysis or data manipulation work.

Let’s do this. Let’s change the world. In this role, you will:

• Lead and develop technical programming and process improvement initiatives within CfOR
• Design, build, and maintain programming solutions and tools that improve efficiency and quality across CfOR’s programming ecosystem.
• Contribute to the full solution development lifecycle—from requirements gathering and design through testing, deployment, and maintenance.
• Collaborate with programming teams across CfOR to identify process gaps and prototype scalable solutions using modern programming practices.
• Support federated innovation—integrating ideas and code contributions from other programming teams into unified, CfOR-wide solutions.
• Automate repeatable programming tasks and establish standards for modular, reusable code.
• Leverage AI and machine learning capabilities, including developing and deploying AI agents or copilots, to optimize programming workflows and knowledge sharing.
• Review and approve clear, version-controlled documentation, training materials, and user guides to enable sustainable adoption of new tools.
• Participate in ongoing evaluation and enhancement of tools, ensuring continued performance, security, and relevance.
• Collaborate with cross-functional partners to align innovations with business needs and technical standards.
• Oversee the work of outsourced resources assigned to projects
• Participate in the recruitment of programming staff
• Manage staff performance and oversee staff assignments and utilization

We are all different, yet we all use our unique contributions to serve patients. This individual contributor programming role will collaborate with teams across multiple time zones to fulfill requests, clarify requirements, escalate issues, and deliver high-quality results.

What we seek in you as a professional are these qualifications and competencies:

Basic Qualifications:

• Bachelor’s degree in Computer Science, Statistics, Mathematics, Life Sciences, or related field.
• At least six (6) years of relevant experience in statistical programming, data engineering, or software development in a life sciences or research setting.
• Proficiency in SAS and/or R, with additional experience in SQL and Python.
• Managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources in Innovation programming projects

Preferred Qualifications:

• Master’s degree in Computer Science, Statistics, Data Science, or related field.
• Experience developing or maintaining solutions through a structured software development lifecycle (SDLC).

• Working with real-world healthcare data (RWD) such as healthcare claims (e.g., MarketScan, Optum Clinformatics, Medicare) and EHR databases (e.g., OptumEHR PanTher, Flatiron, CPRD, MDV)
• Working knowledge of common data model standardization frameworks (e.g., CDISC).
• Working knowledge of version control (e.g., Git) and collaborative coding practices.
• Familiarity with AI and machine learning frameworks (e.g., OpenAI API, or custom model training).
• Leading AI-driven programming assistants, copilots, or agents for workflow optimization.
• Working knowledge of Agile project management and collaborative development environments.

• Strong programming (e.g., SAS, R, SQL, Python) and analytic skills
• Innovation and problem solving
• Strong documentation and communication skills
• Collaboration and teamwork across functions
• Organization and follow-through in structured projects
• AI and automation mindset
• Learning agility and curiosity
• Excellent verbal and written communication skills in English
• Ability to have efficient exchanges with colleagues across geographical locations
• Agile project management
• Leadership
• Innovation
• Teamwork
• Problem solving
• Attention to detail

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

In addition to a competitive base salary, Amgen offers comprehensive Total Rewards plans aligned with industry standards.

Join us. Together, we’ll transform how we program, discover, and deliver the next generation of evidence.